Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate
1-Boc-4-[methoxy(methyl)carbamoyl]piperidine
CAS: 139290-70-3
Molecular Formula: C13H24N2O4
Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate - Names and Identifiers
Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate - Physico-chemical Properties
| Molecular Formula | C13H24N2O4 |
| Molar Mass | 272.34 |
| Density | 1.106±0.06 g/cm3(Predicted) |
| Melting Point | 71.0 to 75.0 °C |
| Boling Point | 150°C/0.9mmHg(lit.) |
| Flash Point | 161.723°C |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Methanol |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | pale yellow oily |
| Color | Pale Yellow |
| pKa | -2.31±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.487 |
| MDL | MFCD07368262 |
Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate - Upstream Downstream Industry
Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate - Introduction
1-Boc-4-[methoxy(methyl) carbamoyl] piperidine is an organic compound whose chemical name is tert-butyl 4-(methoxy) amino formylpiperidine-1-carboxylate, often abbreviated as Boc-MAM piperidine.
Nature:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a solid, usually white crystal or crystalline powder. It has high thermal stability and solubility, and can be dissolved in conventional organic solvents.
Use:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a common organic synthesis intermediate. It is commonly used in the synthesis of pharmaceuticals, pesticides, dyes and other organic compounds. It can be used as a protective group or functional group introduction agent, and play an important role in organic synthesis reaction.
Preparation Method:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine can be synthesized by a series of chemical reactions. The specific preparation method may vary depending on the reaction conditions and laboratory requirements. A common synthetic method is the reaction of piperidinyl 4-carbamate with methanol and methylmagnesium iodide, followed by the addition of tert-butylphosphonate in acetonitrile.
Safety Information:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a chemical that requires careful handling in a laboratory or industrial environment. It may be irritating to the eyes and skin, so it is necessary to wear appropriate protective equipment when handling. In addition, proper storage methods should be followed and contact with oxidants and other hazardous chemicals should be avoided. Specific safety operation procedures should be carried out according to the safety regulations of the laboratory or factory. Observe relevant regulations and guidelines when using or disposing of this compound.
Nature:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a solid, usually white crystal or crystalline powder. It has high thermal stability and solubility, and can be dissolved in conventional organic solvents.
Use:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a common organic synthesis intermediate. It is commonly used in the synthesis of pharmaceuticals, pesticides, dyes and other organic compounds. It can be used as a protective group or functional group introduction agent, and play an important role in organic synthesis reaction.
Preparation Method:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine can be synthesized by a series of chemical reactions. The specific preparation method may vary depending on the reaction conditions and laboratory requirements. A common synthetic method is the reaction of piperidinyl 4-carbamate with methanol and methylmagnesium iodide, followed by the addition of tert-butylphosphonate in acetonitrile.
Safety Information:
1-Boc-4-[methoxy (methyl) carbamoyl] piperidine is a chemical that requires careful handling in a laboratory or industrial environment. It may be irritating to the eyes and skin, so it is necessary to wear appropriate protective equipment when handling. In addition, proper storage methods should be followed and contact with oxidants and other hazardous chemicals should be avoided. Specific safety operation procedures should be carried out according to the safety regulations of the laboratory or factory. Observe relevant regulations and guidelines when using or disposing of this compound.
Last Update：2024-04-09 20:52:54
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CAS: 139290-70-3
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Product Name: 1-Boc-4-(Methoxy-Methyl-Carbamoyl)Piperidine Visit Supplier Webpage Request for quotation
CAS: 139290-70-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 139290-70-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate
1,4-Piperidinedicarboxylic acid
DI-TERT-BUTYL ETHER
N-methoxymethylamine
Ethyl 4-piperidinecarboxylate
Isonipecotic acid
DI-TERT-BUTYL ETHER
N-methoxymethylamine
Ethyl 4-piperidinecarboxylate
Isonipecotic acid
Downstream Products for Tert-Butyl 4-(N-Methoxy-N-Methylcarbamoyl)Piperidine-1-Carboxylate